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Michel D'Incan Selected Research

N- (2- diethylaminoethyl)- 6- iodoquinoxaline- 2- carboxamide

4/2022Phase I study of [131I] ICF01012, a targeted radionuclide therapy, in metastatic melanoma: MELRIV-1 protocol.
3/2021Efficacy of Targeted Radionuclide Therapy Using [131I]ICF01012 in 3D Pigmented BRAF- and NRAS-Mutant Melanoma Models and In Vivo NRAS-Mutant Melanoma.
10/2020Immune checkpoint inhibitors reverse tolerogenic mechanisms induced by melanoma targeted radionuclide therapy.
1/2015[¹²³I]ICF01012 melanoma imaging and [¹³¹I]ICF01012 dosimetry allow adapted internal targeted radiotherapy in preclinical melanoma models.

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Michel D'Incan Research Topics

Disease

15Melanoma (Melanoma, Malignant)
04/2022 - 11/2002
8Neoplasms (Cancer)
04/2022 - 10/2005
7Neoplasm Metastasis (Metastasis)
02/2016 - 02/2004
6Pemphigus (Pemphigus Vulgaris)
01/2020 - 02/2007
3Glioma (Gliomas)
12/2009 - 07/2007
3B-Cell Lymphoma (Lymphoma, B Cell)
03/2009 - 05/2004
2Experimental Melanoma
04/2010 - 01/2009
2Bullous Pemphigoid (Pemphigoid)
07/2009 - 01/2002
2Graft vs Host Disease (Graft-Versus-Host Disease)
12/2007 - 02/2003
2Body Weight (Weight, Body)
08/2007 - 01/2002
1Lymphoma (Lymphomas)
01/2022
1Lymphatic Metastasis
03/2021
1Extranodal Extension
03/2021
1Scleromyxedema (Lichen Myxedematosus)
01/2020
1Paraproteinemias (Monoclonal Gammopathy)
01/2020
1Allergic Contact Dermatitis
05/2019
1Muscular Diseases (Myopathy)
05/2017
1Pathologic Complete Response
05/2017
1Whipple Disease (Whipple's Disease)
03/2015
1Fever (Fevers)
03/2015
1Skin Manifestations
03/2015
1Exanthema (Rash)
03/2015
1Delayed Hypersensitivity (Hypersensitivity, Type IV)
02/2015
1Sarcoidosis (Schaumann Disease)
10/2014
1Disease Progression
03/2013
1Acquired angioedema
10/2011
1Infections
08/2011
1Cytopenia
08/2011
1Drug Hypersensitivity Syndrome
08/2010
1Dermatofibrosarcoma
06/2010
1Fibrosarcoma
04/2010
1Pyelonephritis
08/2007
1Sepsis (Septicemia)
08/2007
1Blister (Bulla)
01/2007
1Parkinson Disease (Parkinson's Disease)
01/2007
1Nervous System Diseases (Neurological Disorders)
01/2007
1Dementia (Dementias)
01/2007
1Stroke (Strokes)
01/2007
1Parkinsonian Disorders (Parkinsonism)
01/2007

Drug/Important Bio-Agent (IBA)

10Rituximab (Mabthera)FDA Link
01/2020 - 02/2007
7Adrenal Cortex Hormones (Corticosteroids)IBA
01/2020 - 01/2002
6Proteins (Proteins, Gene)FDA Link
02/2016 - 05/2004
5N'- (2- chloroethyl)- N- (2- (methylsulfonyl)ethyl)- N'- nitrosoureaIBA
12/2009 - 10/2005
4Melanins (Melanin)IBA
04/2022 - 01/2014
4N- (2- diethylaminoethyl)- 6- iodoquinoxaline- 2- carboxamideIBA
04/2022 - 01/2015
4Radioisotopes (Radionuclides)IBA
04/2022 - 01/2014
4Prednisone (Sone)FDA LinkGeneric
05/2017 - 01/2002
3Biological ProductsIBA
01/2020 - 01/2007
3Annexin A1IBA
02/2016 - 01/2009
2benzamideIBA
04/2022 - 01/2014
2DesmogleinsIBA
01/2020 - 03/2013
2Formyl Peptide Receptors (Formyl Peptide Receptor)IBA
02/2016 - 10/2014
2Small Interfering RNA (siRNA)IBA
10/2014 - 01/2009
2RadiopharmaceuticalsIBA
01/2014 - 11/2002
2N- (2- (diethylamino)ethyl)- 2- iodobenzamideIBA
01/2014 - 11/2002
2AutoantibodiesIBA
03/2013 - 12/2008
2matrigelIBA
04/2010 - 01/2009
2Methionine (L-Methionine)FDA Link
12/2009 - 07/2007
1Bexarotene (LGD1069)FDA Link
01/2022
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
03/2021
1Immune Checkpoint InhibitorsIBA
10/2020
1LigandsIBA
10/2020
1EnzymesIBA
01/2020
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
01/2020
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2020
1ImmunosorbentsIBA
01/2020
1CollagenIBA
01/2020
12-methyl-4-isothiazolin-3-oneIBA
05/2019
1SteroidsIBA
03/2015
1Iodine-123IBA
01/2015
1hyaluronate lyase (spreading factor)IBA
10/2014
1Peptides (Polypeptides)IBA
10/2014
1Thalidomide (Thalomid)FDA Link
10/2014
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
05/2014
1Immunoglobulin G (IgG)IBA
03/2013
1Ferritins (Ferritin)IBA
08/2011
1Triglycerides (Triacylglycerol)IBA
08/2011
1Antiviral Agents (Antivirals)IBA
08/2010
1Pharmaceutical PreparationsIBA
08/2010
1Imatinib Mesylate (Gleevec)FDA Link
06/2010
1Pyruvate KinaseIBA
04/2010
1SynteninsIBA
04/2010
1lactate dehydrogenase 1 (LDH1)IBA
04/2010
1Cathepsin DIBA
04/2010
1Galectin 1 (LGALS1)IBA
04/2010
1Creatine Kinase (Creatine Phosphokinase)IBA
01/2009
1Immunoglobulins (Immunoglobulin)IBA
08/2007
1TransferasesIBA
07/2007
1MethyltransferasesIBA
07/2007
1DNA (Deoxyribonucleic Acid)IBA
07/2007

Therapy/Procedure

13Therapeutics
04/2022 - 01/2002
3Photopheresis
12/2007 - 06/2002
2Immunotherapy
10/2020 - 12/2008
2Drug Therapy (Chemotherapy)
03/2009 - 10/2005
1Aftercare (After-Treatment)
01/2020
1Tattooing
02/2015
1Radiotherapy
01/2015
1Combination Drug Therapy (Combination Chemotherapy)
05/2014
1Transplantation
12/2007
1Contraindications
08/2007